Epidural Block for Cesarean Section. A Comparative Study between 0.5% Racemic Bupivacaine (S50-R50) and 0.5% Enantiomeric Excess Bupivacaine (S75-R25) Associated with Sufentanil
نویسندگان
چکیده
منابع مشابه
Comparative study between 0.125% racemic bupivacaine (S50-R50) and 0.125% and 0.25% of 50% enantiomeric excess bupivacaine in epidural block for labor analgesia.
The study by Duarte et al. 1 confirmed the theoretical fundaments by which enantiomeric excess bupivacaine or enantiomeric mixture of bupivacaine was developed. When we developed this drug, we geared the pre-clinical phase to study whether handling of the isomers regarding their ability to block the nerve would be possible. For such, the mice sciatic nerve was used. Once confirmed the activity ...
متن کامل50% enantiomeric excess hyperbaric bupivacaine (S75:R25) for infraumbilical surgeries. Study with different volumes.
BACKGROUND AND OBJECTIVES Hyperbaric bupivacaine is commercially available in its racemic form. In Brazil, 50% enantiomeric excess bupivacaine (S75:R25) was introduced as an isobaric presentation. The objective of this study was to evaluate different volumes of hyperbaric S75:R25 bupivacaine in spinal blocks for infraumbilical surgeries. METHODS Forty patients, ages 20 to 60 years, physical s...
متن کامل[Comparative study of 0.5% racemic bupivacaine versus enantiomeric mixture (S75-R25) of 0.5% bupivacaine in brachial plexus block for orthopedic surgery.].
BACKGROUND AND OBJECTIVES Several studies were performed with bupivacaine isomers in the attempt to find a safer drug than racemic bupivacaine. This study aimed at evaluating the efficacy of 0.5% bupivacaine enantiomeric mixture (MEE50%) as compared to 0.5% racemic bupivacaine in brachial plexus block for upper limb orthopedic surgery. METHODS Participated of this randomized double-blind stud...
متن کاملComparative study related to cardiovascular safety between bupivacaine (S75-R25) and ropivacaine in brachial plexus block.
BACKGROUND AND OBJECTIVES Bupivacaine is a fi rst choice for regional anesthesia considering its effectiveness, long duration and less motor blockade. Bupivacaine (S75-R25) is a mixture of optical isomers containing 75% levobupivacaine (S-) and 25% dextrobupivacaine (R+) created by a Brazilian pharmaceutical company. This investigation compared cardiac safety and efficacy of bupivacaine S75-R25...
متن کاملEstudo Comparativo entre Bupivacaína a 0,5% e Mistura Enantiomérica de Bupivacaína (S75-R25) a 0,5% em Anestesia Peridural * Comparative Study between 0.5% Bupivacaine and 0.5% Enantiomeric Mixture of Bupivacaine (S75-R25) in Epidural Anesthesia
Justificativa e Objetivos A mistura enantiomérica de bupivacaína (S75-R25) vem sendo empregada pela sua propriedade anestésica com menor toxicidade do que a bupivacaína racêmica. O objetivo deste estudo é comparar a bupivacaína a 0,5% com a mistura enantiomérica de bupivacaína a 0,5% (S75-R25) em anestesia peridural. Método Foram incluídos no estudo 44 pacientes divididos em dois grupos (n=22) ...
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ژورنال
عنوان ژورنال: Brazilian Journal of Anesthesiology
سال: 2009
ISSN: 0034-7094
DOI: 10.1590/s0034-70942009000300001